BodyCap的e-Celsius體溫測量膠囊是一款可連續監測、記錄并無線傳輸核*心體溫信號的微型膠囊。

體溫膠囊經口腔攝入進入體內通過胃、腸道由排出。膠囊自身具有記憶功能測量對象無需佩戴任何監測器而進行無限制的測量。使用簡單方便用于多個科研領域。我們還有動物的核心體溫膠囊。

外部溫度和環境濕度會將與物理力有關的熱應力放大人體體溫調節機制的飽和系統性地導致性能下降并可迅速導致體溫過高。基于可攝取電子膠囊的e-Celsius Performance®解決方案可實現對核心體溫的連續監測。系統能夠識別和傳輸溫度并連續記錄人體的核*心溫度在1米范圍之內都可以收集到可靠的實驗數據。

在運行項目的應用中很多項目都具備測試條件特別是有氧運動為主的項目如自行車長跑鐵人三項；也可應用于橄欖球和跳水項目。

多種規格可供選擇有專門的人體型號也有多種用于實驗室大鼠、小鼠、比格犬等動物的型號。

體溫膠囊的主要特點

· 體積小巧食用方便對機體無損害；

· 實時、連續、監測；

· 無線無導管測量測試對象亦無需實時佩戴監測器實現無限制測量方案；

· 膠囊內置存儲記憶功能可存儲多達2000組數據無需擔心數據丟失；

· 監測器可同時監測3枚膠囊數據且自身可多達7臺并聯實現高通量測量；

主要技術參數

· 人用體溫膠囊經口服攝入通過消化道排泄體內時間1-2天（因人而異）

· 測量參數測量溫度范圍25-45℃精確度0.02℃采樣頻率30Hz（可設定）內部可存儲2000組數據；

· 傳輸參數傳輸距離1m傳輸頻率433Hz；

· 規格參數17.7*8.9mm重1.7g可存儲時間1年開始使用后20天；

· 可同時監測并顯示3枚膠囊傳輸數據并可通過PC/MAC觀察分析；

· 每臺監測器可存儲80000組數據；

主要應用領域

· 體溫過低/高溫中暑預防體溫測量降低低溫/高溫惡劣環境損害或加強對發熱、寒戰等的感知；

· 運動熱身/恢復監測監測人體鍛煉各階段體溫的變化有助于判斷機體運動技能；

· 技能評估、優化用于評估機體體溫調節或心臟節律調節功能等；

· 量化、預防、規避時差影響監測體溫晝夜節律變化制定合理作息從而規避時差影響等；

· 睡眠、晝夜節律和運動表現分析通過體溫變化反映機體睡眠、晝夜節律、運動等規律。

參考文獻

1. Michael Douglas Reed et al., (2019)“IL-17a promotes sociability in mouse models of neurodevelopmental disorders" Nature doi:10.1038/s41586-019-1843-6

2. Topilko T et al.,(2022) “ Edinger-Westphal peptidergic neurons enable maternal preparatory nesting" Neuron doi:10.1016/j.neuron.2022.01.012

3. NPJ Vaccines et al., (2022) “Safety and immunogenicity of four-segmented Rift Valley fever virus in the common marmoset" NPJ Vaccines DOI10.1038/s41541-022-00476-y

4. Laperrousaz et al., (2018) “Lipoprotein Lipase Expression in Hypothalamus is involved in the Central Regulation of Thermogenesis and the Response to Cold Exposure" Frontiers in Endocrinology doi10.3389/fendo.2018.00103

5. Meyer et al., (2017) “Body Temperature Measurements for Metabolic Phenotyping in Mice" Frontiers in Endocrinology doi10.3389/fendo.2018.00103

6. Ru?ange et al., (2020) “Pre-warming before general anesthesia with iso?urane delays the onset of hypothermia in rats" PLoS One doi10.1371/journal.pone.0219722

7. Tattersall et al., (2016) “Novel energy-saving strategies to multiple stressors in birdsthe ultradian regulation of body temperature" P Roy Soc B-Biol Sci doi10.1098/rspb.2022.0526 

8. Schulze et al., (2018) “Body temperature of bitches in the ?rst week after parturition measured by ingestible loggers" Reproduction in Domestic Animals doi:10.1111/rda.13330

9. Guisle et al., (2020) “Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature" Sleep doi:10.1093/sleep/zsz266

10. Thi Cuc Mai et al.,(2021) “Low-Level Radiofrequency Exposure Induces Vasoconstriction in Rats." Sci Rep DOI10.1002/bem.22350 

eCelsius

11. Mart Toots et al., (2019) “Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia Sci Transl Med "doi:10.1016/j.xcrm.2021.100408

12. van Maanen L et al., (2019) “Core body temperature speeds up temporal processing and choice behavior under deadlines" Sci Rep doi:10.1038/s41598-019-46073-3

13. Marine Alhammoud et al.,(2021)“Thermoregulation and shivering responses in elite alpine skiers" Eur J Sport Sci doi:10.1080/.2020.1754470

14. Christopher J. Stevens et al.,(2018) “Effect of two-weeks endurance training wearing additional clothing in a temperate outdoor environment on performance and physiology in the heat " Temperature (Austin) doi:10.1080/.2018.1474672